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Multiple SNPs Within and Surrounding the Apolipoprotein E Gene Influence Cerebrospinal Fluid Apolipoprotein E Protein Levels

The ε4 allele of the apolipoprotein E gene (APOE) is associated with increased risk and earlier age at onset in late onset Alzheimer’s disease (AD). Other factors, such as expression level of apolipoprotein E protein (apoE), have been postulated to modify the APOE related risk of developing AD. Mult...

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Detalhes bibliográficos
Main Authors: Bekris, Lynn M., Millard, Steven P., Galloway, Nichole M., Vuletic, Simona, Albers, John J., Li, Ge, Galasko, Douglas R., DeCarli, Charles, Farlow, Martin R., Clark, Chris M., Quinn, Joseph F., Kaye, Jeffrey A., Schellenberg, Gerard D., Tsuang, Debby, Peskind, Elaine R., Yu, Chang-En
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192652/
https://ncbi.nlm.nih.gov/pubmed/18430993
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