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APP Processing Genes and Cerebrospinal Fluid APP Cleavage Product Levels in Alzheimer’s Disease

The aim of this exploratory investigation was to determine if genetic variation within APP or its processing enzymes correlates with APP cleavage product levels: APPα, APPβ or Aβ42, in cerebrospinal fluid (CSF) of cognitively normal subjects or Alzheimer’s disease (AD) patients. Cognitively normal c...

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Detalhes bibliográficos
Main Authors: Bekris, L.M., Galloway, N.M., Millard, S., Lockhart, D., Li, G., Galasko, D.R., Farlow, M.R., Clark, C.M., Quinn, J.F., Kaye, J.A., Schellenberg, G.D., Leverenz, J.B., Seubert, P., Tsuang, D.W., Peskind, E.R., Yu, C.E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065534/
https://ncbi.nlm.nih.gov/pubmed/21196064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.10.020
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