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Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis

BACKGROUND: Antibodies binding to cartilage proteins are present in the blood and synovial fluid of early rheumatoid arthritis patients. In order to develop animal models mimicking the human disease, we have characterized the arthritogenic capacity of monoclonal antibodies directed towards different...

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Bibliographische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Li, Yanpeng, Tong, Dongmei, Liang, Peibin, Lönnblom, Erik, Viljanen, Johan, Xu, Bingze, Nandakumar, Kutty Selva, Holmdahl, Rikard
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245816/
https://ncbi.nlm.nih.gov/pubmed/32448385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02169-0
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