Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage

Today, it is known that autoimmune diseases start a long time before clinical symptoms appear. Anti-citrullinated protein antibodies (ACPAs) appear many years before the clinical onset of rheumatoid arthritis (RA). However, it is still unclear if and how ACPAs are arthritogenic. To better understand...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ge, Changrong, Tong, Dongmei, Liang, Bibo, Lönnblom, Erik, Schneider, Nadine, Hagert, Cecilia, Viljanen, Johan, Ayoglu, Burcu, Stawikowska, Roma, Nilsson, Peter, Fields, Gregg B., Skogh, Thomas, Kastbom, Alf, Kihlberg, Jan, Burkhardt, Harald, Dobritzsch, Doreen, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499374/
https://ncbi.nlm.nih.gov/pubmed/28679953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93688
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