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The use of Matrigel combined with encapsulated cell technology to deliver a complement inhibitor in a mouse model of choroidal neovascularization

PURPOSE: Risk for age-related macular degeneration (AMD), a slowly progressing, complex disease, is tied to an overactive complement system. Efforts are under way to develop an anticomplement-based treatment to be delivered locally or systemically. We developed an alternative pathway (AP) inhibitor...

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Vydáno v:Mol Vis
Hlavní autoři: Annamalai, Balasubramaniam, Parsons, Nathaniel, Brandon, Carlene, Rohrer, Bärbel
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Vision 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245607/
https://ncbi.nlm.nih.gov/pubmed/32476817
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