INHIBITION OF THE ALTERNATIVE COMPLEMENT PATHWAY ACCELERATES REPAIR PROCESSES IN THE MURINE MODEL OF CHOROIDAL NEOVASCULARIZATION.

Age-related macular degeneration (AMD) is the leading cause of blindness in the US. Polymorphisms in complement components are associated with increased AMD risk, and it has been hypothesized that an overactive complement system is partially responsible for AMD pathology. Choroidal neovascularizatio...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Immunol
Hauptverfasser: Parsons, Nathaniel, Annamalai, Balasubramaniam, Obert, Elisabeth, Schnabolk, Gloriane, Tomlinson, Stephen, Rohrer, Bärbel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538295/
https://ncbi.nlm.nih.gov/pubmed/30763805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2019.02.001
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