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Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization
Complement activation plays a significant role in age-related macular degeneration (AMD) pathogenesis, and polymorphisms interfering with factor H (fH) function, a complement alternative pathway (AP) inhibitor, are associated with increased AMD risk. We have previously validated an AP inhibitor, a f...
שמור ב:
| הוצא לאור ב: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Gene & Cell Therapy
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723362/ https://ncbi.nlm.nih.gov/pubmed/29234687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.11.003 |
| תגים: |
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