HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation

Human telomerase RNA component hTERC comprises multiple motifs that contribute to hTERC biogenesis, holoenzyme activity, and enzyme recruitment to telomeres. hTERC contains several guanine tracts (G-tracts) at its 5′-end, but its associated proteins and potential roles in telomerase function are sti...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Xu, Chenzhong, Xie, Nan, Su, Yuanyuan, Sun, Zhaomeng, Liang, Yao, Zhang, Na, Liu, Doudou, Jia, Shuqin, Xing, Xiaofang, Han, Limin, Li, Guodong, Tong, Tanjun, Chen, Jun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244589/
https://ncbi.nlm.nih.gov/pubmed/31863069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0483-6
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