HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation

Human telomerase RNA component hTERC comprises multiple motifs that contribute to hTERC biogenesis, holoenzyme activity, and enzyme recruitment to telomeres. hTERC contains several guanine tracts (G-tracts) at its 5′-end, but its associated proteins and potential roles in telomerase function are sti...

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Udgivet i:Cell Death Differ
Main Authors: Xu, Chenzhong, Xie, Nan, Su, Yuanyuan, Sun, Zhaomeng, Liang, Yao, Zhang, Na, Liu, Doudou, Jia, Shuqin, Xing, Xiaofang, Han, Limin, Li, Guodong, Tong, Tanjun, Chen, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244589/
https://ncbi.nlm.nih.gov/pubmed/31863069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0483-6
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