hnRNP A1 antagonizes cellular senescence and senescence‐associated secretory phenotype via regulation of SIRT1 mRNA stability

Senescent cells display a senescence‐associated secretory phenotype (SASP) which contributes to tumor suppression, aging, and cancer. However, the underlying mechanisms for SASP regulation are not fully elucidated. SIRT1, a nicotinamide adenosine dinucleotide‐dependent deacetylase, plays multiple ro...

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Gepubliceerd in:Aging Cell
Hoofdauteurs: Wang, Hui, Han, Limin, Zhao, Ganye, Shen, Hong, Wang, Pengfeng, Sun, Zhaomeng, Xu, Chenzhong, Su, Yuanyuan, Li, Guodong, Tong, Tanjun, Chen, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398525/
https://ncbi.nlm.nih.gov/pubmed/27613566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12511
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