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hnRNP A1 associates with telomere ends and stimulates telomerase activity

Telomerase is a ribonucleoprotein enzyme complex that reverse-transcribes an integral RNA template to add short DNA repeats to the 3′-ends of telomeres. G-quadruplex structure in a DNA substrate can block its extension by telomerase. We have found that hnRNP A1—which was previously implicated in tel...

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Detalhes bibliográficos
Main Authors: Zhang, Qing-Shuo, Manche, Lisa, Xu, Rui-Ming, Krainer, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464852/
https://ncbi.nlm.nih.gov/pubmed/16603717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.58806
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