Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing

hnRNP A/B proteins modulate the alternative splicing of several mammalian and viral pre-mRNAs, and are typically viewed as proteins that enforce the activity of splicing silencers. Here we show that intronic hnRNP A/B–binding sites (ABS) can stimulate the in vitro splicing of pre-mRNAs containing ar...

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Main Authors: Martinez-Contreras, Rebeca, Fisette, Jean-François, Nasim, Faiz-ul Hassan, Madden, Richard, Cordeau, Mélanie, Chabot, Benoit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326234/
https://ncbi.nlm.nih.gov/pubmed/16396608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040021
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