Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization

HIV-1-infected infants develop broadly neutralizing antibodies (bnAbs) more rapidly than adults, suggesting differences in the neonatal versus adult responses to the HIV-1 envelope (Env). Here, trimeric forms of HIV-1 Env immunogens elicit increased gp120-and gp41-specific antibodies more rapidly in...

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Publicado no:Cell Rep
Main Authors: Han, Qifeng, Bradley, Todd, Williams, Wilton B., Cain, Derek W., Montefiori, David C., Saunders, Kevin O., Parks, Robert J., Edwards, Regina W., Ferrari, Guido, Mueller, Olaf, Shen, Xiaoying, Wiehe, Kevin J., Reed, Steven, Fox, Christopher B., Rountree, Wes, Vandergrift, Nathan A., Wang, Yunfei, Sutherland, Laura L., Santra, Sampa, Moody, M. Anthony, Permar, Sallie R., Tomaras, Georgia D., Lewis, Mark G., Van Rompay, Koen K.A., Haynes, Barton F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243677/
https://ncbi.nlm.nih.gov/pubmed/32023469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.091
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