Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs

A preventative HIV-1 vaccine is an essential intervention needed to halt the HIV-1 pandemic. Neutralizing antibodies protect against HIV-1 infection in animal models, and thus an approach toward a protective HIV-1 vaccine is to induce broadly cross-reactive neutralizing antibodies (bnAbs). One strat...

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Bibliografski detalji
Izdano u:NPJ Vaccines
Glavni autori: Blasi, Maria, Negri, Donatella, Saunders, Kevin O., Baker, Erich J., Stadtler, Hannah, LaBranche, Celia, Mildenberg, Benjamin, Morton, Georgeanna, Ciarla, Andrew, Shen, Xiaoying, Wang, Yunfei, Rountree, Wes, Balakumaran, Bala, Santra, Sampa, Haynes, Barton F., Moody, Anthony M., Cara, Andrea, Klotman, Mary E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674457/
https://ncbi.nlm.nih.gov/pubmed/33298954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00252-w
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