HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques

Dominant antibody responses in vaccinees who received the HIV-1 multiclade (A, B, and C) envelope (Env) DNA/recombinant adenovirus virus type 5 (rAd5) vaccine studied in HIV-1 Vaccine Trials Network (HVTN) efficacy trial 505 (HVTN 505) targeted Env gp41 and cross-reacted with microbial antigens. In...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Han, Qifeng, Williams, Wilton B., Saunders, Kevin O., Seaton, Kelly E., Wiehe, Kevin J., Vandergrift, Nathan, Von Holle, Tarra A., Trama, Ashley M., Parks, Robert J., Luo, Kan, Gurley, Thaddeus C., Kepler, Thomas B., Marshall, Dawn J., Montefiori, David C., Sutherland, Laura L., Alam, Munir S., Whitesides, John F., Bowman, Cindy M., Permar, Sallie R., Graham, Barney S., Mascola, John R., Seed, Patrick C., Van Rompay, Koen K. A., Tomaras, Georgia D., Moody, M. Anthony, Haynes, Barton F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640856/
https://ncbi.nlm.nih.gov/pubmed/28794027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00923-17
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