Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk

The development of an effective maternal HIV-1 vaccine that could synergize with antiretroviral therapy (ART) to eliminate pediatric HIV-1 infection will require the characterization of maternal immune responses capable of blocking transmission of autologous HIV to the infant. We previously determin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Martinez, David R., Vandergrift, Nathan, Douglas, Ayooluwa O., McGuire, Erin, Bainbridge, John, Nicely, Nathan I., Montefiori, David C., Tomaras, Georgia D., Fouda, Genevieve G., Permar, Sallie R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391478/
https://ncbi.nlm.nih.gov/pubmed/28202762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02422-16
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