HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine

In the RV144 vaccine trial, IgG responses against the HIV envelope variable loops 1 and 2 (V1V2) were associated with decreased HIV acquisition risk. We previously reported that infants immunized with an MF59-adjuvanted rgp120 vaccine developed higher-magnitude anti-V1V2 IgG responses than adult RV1...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: McGuire, Erin P., Fong, Youyi, Toote, Christopher, Cunningham, Coleen K., McFarland, Elizabeth J., Borkowsky, William, Barnett, Susan, Itell, Hannah L., Kumar, Amit, Gray, Glenda, McElrath, M. Julianna, Tomaras, Georgia D., Permar, Sallie R., Fouda, Genevieve G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730786/
https://ncbi.nlm.nih.gov/pubmed/29021402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01070-17
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