HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine

In the RV144 vaccine trial, IgG responses against the HIV envelope variable loops 1 and 2 (V1V2) were associated with decreased HIV acquisition risk. We previously reported that infants immunized with an MF59-adjuvanted rgp120 vaccine developed higher-magnitude anti-V1V2 IgG responses than adult RV1...

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Foilsithe in:J Virol
Main Authors: McGuire, Erin P., Fong, Youyi, Toote, Christopher, Cunningham, Coleen K., McFarland, Elizabeth J., Borkowsky, William, Barnett, Susan, Itell, Hannah L., Kumar, Amit, Gray, Glenda, McElrath, M. Julianna, Tomaras, Georgia D., Permar, Sallie R., Fouda, Genevieve G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Vaccines and Antiviral Agents
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730786/
https://ncbi.nlm.nih.gov/pubmed/29021402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01070-17
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