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Cohesin Causes Replicative DNA Damage by Trapping DNA Topological Stress
DNA topological stress inhibits DNA replication fork (RF) progression and contributes to DNA replication stress. In Saccharomyces cerevisiae, we demonstrate that centromeric DNA and the rDNA array are especially vulnerable to DNA topological stress during replication. The activity of the SMC complex...
में बचाया:
| में प्रकाशित: | Mol Cell |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cell Press
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242899/ https://ncbi.nlm.nih.gov/pubmed/32259483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.013 |
| टैग : |
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