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Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress
The highly conserved Tof1/Timeless proteins minimise replication stress and promote normal DNA replication. They are required to mediate the DNA replication checkpoint (DRC), the stable pausing of forks at protein fork blocks, the coupling of DNA helicase and polymerase functions during replication...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7708041/ https://ncbi.nlm.nih.gov/pubmed/33166393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa963 |
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