Spontaneous glycan reattachment following N-glycanase treatment of influenza and HIV vaccine antigens

In cells asparagine/N-linked glycans are added to glycoproteins co-translationally, in an attachment process that supports proper folding of the nascent polypeptide. We find that following pruning of N-glycan by the amidase PNGase F, the principle influenza vaccine antigen and major viral spike prot...

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Опубликовано в: :J Proteome Res
Главные авторы: Keating, Celina L., Kuhn, Eric, Bals, Julia, Cocco, Alexandra R., Yousif, Ashraf S., Matysiak, Colette, Sangesland, Maya, Ronsard, Larance, Smoot, Matthew, Moreno, Thalia Bracamonte, Okonkwo, Vintus, Setliff, Ian, Georgiev, Ivelin, Balazs, Alejandro B., Carr, Steven A., Lingwood, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241686/
https://ncbi.nlm.nih.gov/pubmed/31913636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00620
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