The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

The interleukin-6 (IL-6) membrane receptor and its circulating soluble form, sIL-6R, can be targeted by antibody therapy to reduce deleterious immune signaling caused by chronic overexpression of the pro-inflammatory cytokine IL-6. This strategy may also hold promise for treating acute hyperinflamma...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Immunity
Autori principali: Yousif, Ashraf S., Ronsard, Larance, Shah, Pankaj, Omatsu, Tatsushi, Sangesland, Maya, Bracamonte Moreno, Thalia, Lam, Evan C., Vrbanac, Vladimir D., Balazs, Alejandro B., Reinecker, Hans-Christian, Lingwood, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2021
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836640/
https://ncbi.nlm.nih.gov/pubmed/33357409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.12.001
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