Engineered receptor binding domain immunogens elicit pan-sarbecovirus neutralizing antibodies outside the receptor binding motif

Effective countermeasures are needed against emerging coronaviruses of pandemic potential, similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Designing immunogens that elicit broadly neutralizing antibodies to conserved viral epitopes on the major surface glycoprotein, spike, s...

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Vydáno v:bioRxiv
Hlavní autoři: Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Denis, Kerri J. St., Feldman, Jared, Yousif, Ashraf S., Caradonna, Timothy M., Kannegieter, Ty, Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743097/
https://ncbi.nlm.nih.gov/pubmed/33330872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.07.415216
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