Engineered receptor binding domain immunogens elicit pan-sarbecovirus neutralizing antibodies outside the receptor binding motif

Effective countermeasures are needed against emerging coronaviruses of pandemic potential, similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Designing immunogens that elicit broadly neutralizing antibodies to conserved viral epitopes on the major surface glycoprotein, spike, s...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Denis, Kerri J. St., Feldman, Jared, Yousif, Ashraf S., Caradonna, Timothy M., Kannegieter, Ty, Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743097/
https://ncbi.nlm.nih.gov/pubmed/33330872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.07.415216
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