Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

Exposure to a pathogen elicits an adaptive immune response aimed to control and eradicate. Interrogating the abundance and specificity of the naive B cell repertoire contributes to understanding how to potentially elicit protective responses. Here, we isolated naive B cells from 8 seronegative human...

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發表在:bioRxiv
Main Authors: Feldman, Jared, Bals, Julia, Altomare, Clara G., St. Denis, Kerri, Lam, Evan C., Hauser, Blake M., Ronsard, Larance, Sangesland, Maya, Moreno, Thalia Bracamonte, Okonkwo, Vintus, Hartojo, Nathania, Balazs, Alejandro B., Bajic, Goran, Lingwood, Daniel, Schmidt, Aaron G.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885909/
https://ncbi.nlm.nih.gov/pubmed/33594359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.02.429458
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