ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 2019(1,2) and is responsible for the COVID-19 pandemic(3). Vaccines are an essential countermeasure urgently needed to control the pandemic(4). Here, we show that the adenovirus-vectored vaccine ChAdOx1 nCoV-19, encodin...

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Vydáno v:bioRxiv
Hlavní autoři: van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria, Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241103/
https://ncbi.nlm.nih.gov/pubmed/32511340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.13.093195
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