ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 2019(1,2) and is responsible for the COVID-19 pandemic(3). Vaccines are an essential countermeasure urgently needed to control the pandemic(4). Here, we show that the adenovirus-vectored vaccine ChAdOx1 nCoV-19, encodin...

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發表在:bioRxiv
Main Authors: van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria, Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7241103/
https://ncbi.nlm.nih.gov/pubmed/32511340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.13.093195
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