Native-like SARS-CoV-2 spike glycoprotein expressed by ChAdOx1 nCoV-19/AZD1222 vaccine

Vaccine development against the SARS-CoV-2 virus focuses on the principal target of the neutralizing immune response, the spike (S) glycoprotein. Adenovirus-vectored vaccines offer an effective platform for the delivery of viral antigen, but it is important for the generation of neutralizing antibod...

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Publicado en:bioRxiv
Main Authors: Watanabe, Yasunori, Mendonça, Luiza, Allen, Elizabeth R., Howe, Andrew, Lee, Mercede, Allen, Joel D., Chawla, Himanshi, Pulido, David, Donnellan, Francesca, Davies, Hannah, Ulaszewska, Marta, Belij-Rammerstorfer, Sandra, Morris, Susan, Krebs, Anna-Sophia, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Supasa, Piyada, Screaton, Gavin R., Green, Catherine M., Lambe, Teresa, Zhang, Peijun, Gilbert, Sarah C., Crispin, Max
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836103/
https://ncbi.nlm.nih.gov/pubmed/33501433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.15.426463
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