ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

Vaccines against SARS-CoV-2 are likely to be critical in the management of the ongoing pandemic. A number of candidates are in Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored vaccine candidate. In preclinical trials, the ef...

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Publié dans:NPJ Vaccines
Auteurs principaux: Marsh, Glenn A., McAuley, Alexander J., Au, Gough G., Riddell, Sarah, Layton, Daniel, Singanallur, Nagendrakumar B., Layton, Rachel, Payne, Jean, Durr, Peter A., Bender, Hannah, Barr, Jennifer A., Bingham, John, Boyd, Victoria, Brown, Sheree, Bruce, Matthew P., Burkett, Kathie, Eastwood, Teresa, Edwards, Sarah, Gough, Tamara, Halpin, Kim, Harper, Jenni, Holmes, Clare, Horman, William S. J., van Vuren, Petrus Jansen, Lowther, Suzanne, Maynard, Kate, McAuley, Kristen D., Neave, Matthew J., Poole, Timothy, Rootes, Christina, Rowe, Brenton, Soldani, Elisha, Stevens, Vittoria, Stewart, Cameron R., Suen, Willy W., Tachedjian, Mary, Todd, Shawn, Trinidad, Lee, Walter, Duane, Watson, Naomi, Drew, Trevor W., Gilbert, Sarah C., Lambe, Teresa, Vasan, S. S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110954/
https://ncbi.nlm.nih.gov/pubmed/33972565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00315-6
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