ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

Vaccines against SARS-CoV-2 are likely to be critical in the management of the ongoing pandemic. A number of candidates are in Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored vaccine candidate. In preclinical trials, the ef...

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Pubblicato in:NPJ Vaccines
Autori principali: Marsh, Glenn A., McAuley, Alexander J., Au, Gough G., Riddell, Sarah, Layton, Daniel, Singanallur, Nagendrakumar B., Layton, Rachel, Payne, Jean, Durr, Peter A., Bender, Hannah, Barr, Jennifer A., Bingham, John, Boyd, Victoria, Brown, Sheree, Bruce, Matthew P., Burkett, Kathie, Eastwood, Teresa, Edwards, Sarah, Gough, Tamara, Halpin, Kim, Harper, Jenni, Holmes, Clare, Horman, William S. J., van Vuren, Petrus Jansen, Lowther, Suzanne, Maynard, Kate, McAuley, Kristen D., Neave, Matthew J., Poole, Timothy, Rootes, Christina, Rowe, Brenton, Soldani, Elisha, Stevens, Vittoria, Stewart, Cameron R., Suen, Willy W., Tachedjian, Mary, Todd, Shawn, Trinidad, Lee, Walter, Duane, Watson, Naomi, Drew, Trevor W., Gilbert, Sarah C., Lambe, Teresa, Vasan, S. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110954/
https://ncbi.nlm.nih.gov/pubmed/33972565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00315-6
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