Effect of the His-Tag Location on Decapping Scavenger Enzymes and Their Hydrolytic Activity toward Cap Analogs

[Image: see text] Decapping scavenger enzymes (DcpSs) are important players in mRNA degradation machinery and conserved in eukaryotes. Importantly, human DcpS is the recognized target for spinal muscular atrophy (SMA) and acute myeloid leukemia (AML) therapy, and has recently been connected to devel...

Full description

Saved in:
Bibliographic Details
Published in:ACS Omega
Main Authors: Ferenc-Mrozek, Aleksandra, Bojarska, Elzbieta, Stepinski, Janusz, Darzynkiewicz, Edward, Lukaszewicz, Maciej
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240826/
https://ncbi.nlm.nih.gov/pubmed/32455195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00304
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items