Decapping Scavenger Enzyme Activity toward N2-Substituted 5′ End mRNA Cap Analogues

[Image: see text] mRNA degradation is a key mechanism of gene expression regulation. In the 3′ → 5′ decay pathway, mRNA is degraded by the exosome complex and the resulting cap dinucleotide or short-capped oligonucleotide is hydrolyzed mainly by a decapping scavenger enzyme (DcpS)—a member of the hi...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Pietrow, Paulina, Ferenc-Mrozek, Aleksandra, Piecyk, Karolina, Bojarska, Elzbieta, Darzynkiewicz, Edward, Jankowska-Anyszka, Marzena
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812366/
https://ncbi.nlm.nih.gov/pubmed/31656932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02715
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