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Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release

Vesicle fusion is mediated by assembly of SNARE proteins between opposing membranes. While previous work suggested an active role of SNARE transmembrane domains (TMDs) in promoting membrane merger (Dhara et al., 2016), the underlying mechanism remained elusive. Here, we show that naturally-occurring...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Dhara, Madhurima, Mantero Martinez, Maria, Makke, Mazen, Schwarz, Yvonne, Mohrmann, Ralf, Bruns, Dieter
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239655/
https://ncbi.nlm.nih.gov/pubmed/32391794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55152
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