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Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion During Neurotransmitter Release
Synaptic vesicle fusion during neurotransmitter release is mediated by assembly of SNARE- and SM-protein complexes composed of syntaxin-1, SNAP-25, synaptobrevin-2/VAMP2, and Munc18-1. Current models suggest that SNARE-complex assembly catalyzes membrane fusion by pulling the transmembrane regions (...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872166/ https://ncbi.nlm.nih.gov/pubmed/24120845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.09.010 |
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