v-SNARE transmembrane domains function as catalysts for vesicle fusion

Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAREpin to the fusing membranes. Here, we show that c...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Dhara, Madhurima, Yarzagaray, Antonio, Makke, Mazen, Schindeldecker, Barbara, Schwarz, Yvonne, Shaaban, Ahmed, Sharma, Satyan, Böckmann, Rainer A, Lindau, Manfred, Mohrmann, Ralf, Bruns, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972536/
https://ncbi.nlm.nih.gov/pubmed/27343350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17571
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