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t-SNARE Transmembrane Domain Clustering Modulates Lipid Organization and Membrane Curvature

[Image: see text] The t-SNARE complex plays a central role in neuronal fusion. Its components, syntaxin-1 and SNAP25, are largely present in individual clusters and partially colocalize at the presumptive fusion site. How these protein clusters modify local lipid composition and membrane morphology...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sharma, Satyan, Lindau, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802331/
https://ncbi.nlm.nih.gov/pubmed/29231734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10677
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