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Molecular mechanism of fusion pore formation driven by the neuronal SNARE complex

Release of neurotransmitters from synaptic vesicles begins with a narrow fusion pore, the structure of which remains unresolved. To obtain a structural model of the fusion pore, we performed coarse-grained molecular dynamics simulations of fusion between a nanodisc and a planar bilayer bridged by fo...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sharma, Satyan, Lindau, Manfred
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294955/
https://ncbi.nlm.nih.gov/pubmed/30482862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816495115
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