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Steroid-based amphiphiles for membrane protein study: Importance of alkyl spacer for protein stability

Membrane proteins allow effective communication between cells and organelles and their external environments. Maintaining membrane protein stability in a non-native environment is the major bottleneck to their structural study. Detergents are widely used to extract membrane proteins from the membran...

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Bibliografische gegevens
Gepubliceerd in:Chembiochem
Hoofdauteurs: Ehsan, Muhammad, Das, Manabendra, Stern, Valerie, Du, Yang, Mortensen, Jonas S., Hariharan, Parameswaran, Byrne, Bernadette, Loland, Claus J., Kobilka, Brian K., Guan, Lan, Chae, Pil Seok
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238963/
https://ncbi.nlm.nih.gov/pubmed/29660780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800106
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