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Total Synthesis and Biological Evaluation of Kakeromamide A and Its Analogues
Kakeromamide A (1), the first marine cyclopeptide inducing neural stem cells differentiation into astrocytes, was synthesized in 12 longest linear steps and 14% overall yield. Using this synthetic approach, four analogs of kakeromamide A were prepared and evaluated for neural differentiation- modula...
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| Pubblicato in: | Front Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7237762/ https://ncbi.nlm.nih.gov/pubmed/32478037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00410 |
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