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Total synthesis and biological evaluation of marinopyrrole A and analogues
A five-step total synthesis of the antibiotic marinopyrrole A (1) is described. The developed synthetic technology enabled the synthesis of several marinopyrrole A analogues whose antibacterial properties against methicillin-resistant Staphylococcus aureus TCH1516 were evaluated.
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077031/ https://ncbi.nlm.nih.gov/pubmed/21499535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.09.059 |
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