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Spatial regulation of GPR64/ADGRG2 signaling by β-arrestins and GPCR kinases
Mechanisms of activation, signaling, and trafficking of adhesion G protein–coupled receptors (aGPCRs) have remained largely unknown. Several aGPCRs, including GPR56/ADGRG1 and GPR64/ADGRG2, show increased activity in the absence of their N-terminal fragment (NTF). This constitutive signaling is plau...
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| Publicado en: | Ann N Y Acad Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236788/ https://ncbi.nlm.nih.gov/pubmed/31502283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14227 |
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