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GPCR signaling via β-arrestin-dependent mechanisms

β-arrestin1 (or arrestin2) and β-arrestin2 (or arrestin3) are ubiquitously expressed cytosolic adaptor proteins that were originally discovered for their inhibitory role in G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins. However, further biochemical characterization reveal...

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Détails bibliographiques
Publié dans:J Cardiovasc Pharmacol
Auteurs principaux: Jean-Charles, Pierre-Yves, Kaur, Suneet, Shenoy, Sudha K.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591062/
https://ncbi.nlm.nih.gov/pubmed/28328745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000482
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