GPCR signaling via β-arrestin-dependent mechanisms

Por Jean-Charles, Pierre-Yves, Kaur, Suneet, Shenoy, Sudha K.
Publicado no J Cardiovasc Pharmacol (2017)

Phosphorylation of the Deubiquitinase USP20 by Protein Kinase A Regulates Post-endocytic Trafficking of β(2) Adrenergic Receptors to Autophagosomes during Physiological Stress

Por Kommaddi, Reddy Peera, Jean-Charles, Pierre-Yves, Shenoy, Sudha K.
Publicado no J Biol Chem (2015)

Insights into restrictive cardiomyopathy from clinical and animal studies

Por Jean-Charles, Pierre-Yves, Li, Yue-Jin, Nan, Chang-Long, Huang, Xu-Pei
Publicado em 2011

Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation

Por Jean-Charles, Pierre-Yves, Zhang, Lisheng, Wu, Jiao-Hui, Han, Sang-oh, Brian, Leigh, Freedman, Neil J., Shenoy, Sudha K.
Publicado no J Biol Chem (2016)

Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations

Por Li, Yuejin, Zhang, Lei, Jean-Charles, Pierre-Yves, Nan, Changlong, Chen, Guozhen, Tian, Jie, Jin, J.-P., Gelb, Ira J., Huang, Xupei
Publicado no J Mol Cell Cardiol (2013)

Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI

Por Du, Jianfeng, Liu, Jing, Feng, Han-Zhong, Hossain, M. M., Gobara, Nariman, Zhang, Chi, Li, Yuejin, Jean-Charles, Pierre-Yves, Jin, Jian-Ping, Huang, Xu-Pei
Publicado em 2008

Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling

Por Jean-Charles, Pierre-Yves, Yu, Samuel Mon-Wei, Abraham, Dennis, Kommaddi, Reddy Peera, Mao, Lan, Strachan, Ryan T., Zhang, Zhu-Shan, Bowles, Dawn E., Brian, Leigh, Stiber, Jonathan A., Jones, Stephen N., Koch, Walter J., Rockman, Howard A., Shenoy, Sudha K.
Publicado no JCI Insight (2017)