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Phosphorylation of the Deubiquitinase USP20 by Protein Kinase A Regulates Post-endocytic Trafficking of β(2) Adrenergic Receptors to Autophagosomes during Physiological Stress
Ubiquitination by the E3 ligase Nedd4 and deubiquitination by the deubiquitinases USP20 and USP33 have been shown to regulate the lysosomal trafficking and recycling of agonist-activated β(2) adrenergic receptors (β(2)ARs). In this work, we demonstrate that, in cells subjected to physiological stres...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423680/ https://ncbi.nlm.nih.gov/pubmed/25666616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.630541 |
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