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The deubiquitinases USP33 and USP20 coordinate β(2) adrenergic receptor recycling and resensitization

Agonist-induced ubiquitination of the β(2) adrenergic receptor (β(2)AR) functions as an important post-translational modification to sort internalized receptors to the lysosomes for degradation. We now show that this ubiquitination is reversed by two deubiquitinating enzymes, ubiquitin-specific prot...

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Detalhes bibliográficos
Main Authors: Berthouze, Magali, Venkataramanan, Vidya, Li, Yi, Shenoy, Sudha K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699358/
https://ncbi.nlm.nih.gov/pubmed/19424180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.128
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