Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling

Abnormal feedback of serum calcium to parathyroid hormone (PTH) secretion is the hallmark of primary hyperparathyroidism (PHPT). Although the molecular pathogenesis of parathyroid neoplasia in PHPT has been linked to abnormal expression of genes involved in cell growth (e.g., cyclin D1, retinoblasto...

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Bibliografske podrobnosti
izdano v:J Bone Miner Res
Main Authors: Balenga, Nariman, Azimzadeh, Pedram, Hogue, Joyce A, Staats, Paul N, Shi, Yuhong, Koh, James, Dressman, Holly, Olson, John A
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211037/
https://ncbi.nlm.nih.gov/pubmed/27760455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3023
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