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Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling

Abnormal feedback of serum calcium to parathyroid hormone (PTH) secretion is the hallmark of primary hyperparathyroidism (PHPT). Although the molecular pathogenesis of parathyroid neoplasia in PHPT has been linked to abnormal expression of genes involved in cell growth (e.g., cyclin D1, retinoblasto...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Balenga, Nariman, Azimzadeh, Pedram, Hogue, Joyce A, Staats, Paul N, Shi, Yuhong, Koh, James, Dressman, Holly, Olson, John A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211037/
https://ncbi.nlm.nih.gov/pubmed/27760455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3023
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