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Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling

Abnormal feedback of serum calcium to parathyroid hormone (PTH) secretion is the hallmark of primary hyperparathyroidism (PHPT). Although the molecular pathogenesis of parathyroid neoplasia in PHPT has been linked to abnormal expression of genes involved in cell growth (e.g., cyclin D1, retinoblasto...

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Dades bibliogràfiques
Publicat a:J Bone Miner Res
Autors principals: Balenga, Nariman, Azimzadeh, Pedram, Hogue, Joyce A, Staats, Paul N, Shi, Yuhong, Koh, James, Dressman, Holly, Olson, John A
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211037/
https://ncbi.nlm.nih.gov/pubmed/27760455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3023
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