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Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2

Cleavage and dissociation of a large N-terminal fragment and the consequent unmasking of a short sequence (Stachel) remaining on the N-terminus have been proposed as mechanisms of activation of some members of the adhesion G protein-coupled receptor (aGPCR) family. However, the identity of residues...

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Publicado en:Sci Rep
Main Authors: Gad, Abanoub A., Azimzadeh, Pedram, Balenga, Nariman
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263569/
https://ncbi.nlm.nih.gov/pubmed/34234254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93577-y
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