5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein

[Image: see text] The HIV-1 nucleocapsid (NC) protein is a small basic DNA and RNA binding protein that is absolutely necessary for viral replication and thus represents a target of great interest to develop new anti-HIV agents. Moreover, the highly conserved sequence offers the opportunity to escap...

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Malancona, Savina, Mori, Mattia, Fezzardi, Paola, Santoriello, Marisabella, Basta, Andreina, Nibbio, Martina, Kovalenko, Lesia, Speziale, Roberto, Battista, Maria Rosaria, Cellucci, Antonella, Gennari, Nadia, Monteagudo, Edith, Di Marco, Annalise, Giannini, Alessia, Sharma, Rajhans, Pires, Manuel, Real, Eleonore, Zazzi, Maurizio, Dasso Lang, Maria Chiara, De Forni, Davide, Saladini, Francesco, Mely, Yves, Summa, Vincenzo, Harper, Steven, Botta, Maurizio
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2020
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236274/
https://ncbi.nlm.nih.gov/pubmed/32435383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00608
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