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Agreement between an in‐house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV‐1 protease, reverse transcriptase, and integrase inhibitors

BACKGROUND: Although clinical management of drug resistance is routinely based on genotypic methods, phenotypic assays remain necessary for the characterization of novel HIV‐1 inhibitors, particularly against common drug‐resistant variants. We describe the development and assessment of the performan...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Saladini, Francesco, Giannini, Alessia, Boccuto, Adele, Vicenti, Ilaria, Zazzi, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816933/
https://ncbi.nlm.nih.gov/pubmed/28303602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22206
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